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Description
AMPK antagonizes mammalian target of rapamycin (mTOR) activity, and its downstream effector, p27, inhibits cyclin-dependent kinase 2 (CDK2), thereby blocking the G1/S transition in the cell cycle, halting cell division, and subsequently inhibiting cellular proliferation [57]
Cell Metab 24(1):5162
What Is GLP-1 Therapy and How Does It Work
Studies were conducted with 3- to 4-year time frames between 2005 and 2013
