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Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury
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Most semaglutide doses deliver less than 1 milliliter of medication, a small amount that enters slowly enough to minimize pressure buildup at the injection site
Compared with GLP-1 RAs, more participants receiving tirzepatide 15 mg discontinued treatment due to adverse events (OR 2.29 [95% CI 1.39, 3.75], I 2 0%), whereas no difference was evident for tirzepatide 5 mg and 10 mg (ESM Table 3)
