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Additional hypotheses include transient increases in pancreatic ductal pressure, local enzyme activation, and inflammatory cytokine modulation, though these lack definitive mechanistic evidence [6,9]

As it involved anonymised retrospective data review without direct patient contact, formal research ethics approval was not required under NHS Health Research Authority guidance

Obesity wonder drugs Wegovy and Zepbound are already showing that they can reduce the risk of cardiovascular and chronic kidney disease in addition to helping people lose weight

If a pen is left out of the refrigerator, it can be stored at room temperature (up to 30C) for up to 21 days