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Methylation The Pathway Pathway Description Dietary folates are normally ingested as polyglutamates, which require deconjugation to monoglutamates by the enzyme, folyl polyglutamate carboxypeptidase (FGCP), prior to absorption, in order to be transported

2H and Supplementary Fig

There are numerous reasons for an altered microglial secretory profile in aging, but one specific to white matter regions could be an increase in myelin debris that cannot be efficiently cleared/metabolized by microglia, resulting in cellular stress (Safaiyan et al., 2016)

Genetic (allelic) heterogeneity of G6PD deficiency There are now 187 known mutations in the G6PD gene (Minucci et al , 2012a), and at least 35 of the mutant alleles are polymorphic, i.e