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The significant upregulation of CHOP, along with the induction of apoptotic proteins (PARP/cleaved PARP, AIF, caspase-3) and the inhibition of antiapoptotic Bcl-2, indicates the activation of both intrinsic and extrinsic apoptotic pathways

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( A ) Plasma d 3 -TMAO and d 3 -BB concentrations in vegans/vegetarians (d 3 -TMAO, n = 9

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4,650,759 and 5,248,601, and EP 457,735)

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Laboratory diagnostics of the serum, urine or muscle acetylcarnitine level can be performed to diagnose L-carnitine deficiency with certainty

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