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CF airways feature intense inflammation and high H 2 O 2 production from phagocytes (Galli et al., 2012)

Despite their potential to ameliorate neurodegeneration through upregulation of NRF2 and its target genes, as shown by numerous pre-clinical studies, their molecular off-target effects and concomitant unpredictable side-effects pose an obstacle for clinical trials and approval

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Int J Oral Sci 18 , 49 (2026)
