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Hypoxia inducible factors (HIFs) mediate the transcription of multiple genes that allow cells to adapt to hypoxic environments, increase in cancer with a poor prognosis, and participate in various stages of carcinogenesis and cancer progression (194)
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Thus, the efficacy of SSRIs demonstrates that 5-HT may be highly implicated in depression
The reaction was proceeded for 2 h at 130 C under inert gas
