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Model analysis Selection of parameters for estimation The methodology to select parameters for estimation involves first conducting local sensitivity analysis (LSA) to obtain a set of important parameters, and then determining from this set of parameters which are identifiable, that is for which parameters a value can be identified from the data, taking into account the model structure

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Allergic reactions to glutathione are uncommon but possible

The nodes of Ranvier are unmyelinated sections of the axon that have a high density of voltage-gated sodium (Na v ) channels that respond rapidly to alterations in charge and function to propagate signals necessary for the depolarization of the next node during an action potential (Arancibia-Carcamo and Attwell, 2014)