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Such unwanted side effects include undesired tachycardia, increased lactic acidosis, cardiac arrhythmias (including atrial fibrillation) as well as the development of refractory shock (DeBacker et al, 2010
Molecules 26, 5537
In a clinical trial in 42 individuals with type 2 diabetes, 300 mg of a chlorogenic acid-containing plant extract daily for four weeks significantly reduced fasting plasma glucose, C-reactive protein (CRP), and liver enzymes compared with placebo (Abidov 2006)
But it is not excluded that also three (or four) Cys residues could be labeled with methoxypolyethylene glycol maleimide (mPEG-MAL)-5000, due to the broader difference in molecular mass of the immune-reacting GSAAT-band with zero (0) or one (1) cysteine bound to mPED-MAL
