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Annals of Clinical and Laboratory Science (2015) 6

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Beyond the ENS, this transcriptional factor when selectively activated by the microbial metabolite indole produced by tryptophanase-expressing gut microbes interestingly induces neurogenic effects in the adult murine hippocampus as identified by elevated expression of -catenin, Neurog2, and VEGF- (Wei et al., 2021)