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AOD-9604 demonstrates selectivity for beta-3 receptors, which are predominantly expressed in adipose tissue

Results were presented as mean SD

smoking more than 40 pack years of cigarettes was associated with an odds ratio of 3.43 for dry AMD and 2.49 for wet AMD

Moreover, metabolomic analyses show that HIF1 overexpression results in increased levels of PPP metabolites in murine BMDMs (193)
