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Dysregulation in the GSH homeostasis has been associated with tumor progression and therapy resistance [2]

Such dysregulation results in a disruption of the pulsatile secretion of gonadotropin-releasing hormone by the hypothalamus, which in turn leads to abnormal gonadotropin secretion

Coordinates have been deposited to the PDB with accession codes 9EXG, 9EX5, 9EXF, 9EXT and 9EYT

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