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To explain the heat-sensitive phenotype, it was proposed that ACDH-11 would sequester C 10 -C 12 -straight-chain fatty acids that activate NHR-49, thereby downregulating expression of fat-7 (Fig

Normally, more than 99% of stored enzyme is secreted into the pancreatic duct and less than 1% diffuses across cell membranes and reaches the circulation via lymphatics and capillaries

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