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IL-8, a key neutrophil chemoattractant, binds to CXCR1 and CXCR2 receptors on neutrophil surfaces, promoting their chemotaxis and infiltration into the liver [75]

The radiosensitization potential of coated NPs is confirmed by numerous studies but in most of them the coating layer is mostly applied for reducing toxicity of the NPs and for stability and biocompatibility aims

Third, while radiation exposure has been linked to DSBs and other types of DNA damage, there is no long-term data that proves a reduction in DSBs leads to a reduction in carcinogenesis and teratogenesis

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