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Description
Comprising 15 amino acids from the C-terminus end of Growth Hormone Polypeptide (GH), AOD 9604 is unique in its impact on insulin levels and its dual action in stimulating lipolysis (fat breakdown) and inhibiting lipogenesis (fat accumulation)

Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue

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