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When treated with H 2 O 2 (500 M, 2 h), GPx1-KD macrophages displayed increased cytotoxicity compared to cells treated with the nsSiRNA (Fig
Nevertheless, pyridoxal phosphate and pyridoxamine phosphate are the active endogenous metabolites of vitamin B6 that are involved in various biochemical reactions, including the metabolism of macronutrients, synthesis of nucleic acids, hemoglobin, and neurotransmitters (52, 53)
Clin Cancer Res 21(11):2644-51, 2015
