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In human populations, selenium deficiency, due to lack of selenium in the soil, has been found to cause Keshan disease (6, 138, 216, 305), a cardiomyopathy, and Kashin-Beck disease (287, 393), an osteoarthropathy, in part, due to reductions in GPx-1 expression

Transmission electron microscopy (TEM) showed that the mitochondria of hair follicle cells in the anagen are thinner and longer than those in the telogen, while the mitochondria in the telogen are more swollen, and the mitochondria in the anagen have more abundant cristae [11]

By contrast, a porcine enzyme entitled SscGST A2-2, linked to ovarian follicular differentiation and showing 84% sequence identity with the human enzyme, was found to approach the high ketosteroid activity of HsaGST A3-3 (Ismail et al., 2021)

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