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At baseline, we observed a lower puromycin incorporation in pp65 495503 specifc CD8 + T cells in noncontrollers than in controllers underscoring the reduced expression of ATP5a as part of ETC complex V, which is the main ATP generator in resting memory CD8 + T cells (26) (Supplemental Figure 3I)

Some of the limitations of this study included the sample size, length of observation, and a variety of tumor sources

Improved insulin sensitivity also reduces the risk of developing metabolic diseases and supports better overall metabolic health