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This activation converts pro-interleukin-1 (pro-IL-1) and pro-interleukin-18 (pro-IL-18) into their active forms, which are subsequently released extracellularly, initiating sustained inflammation that disrupts neural circuits and promotes both seizures and depressive behaviors

Gene Expression Analysis Gene expression analysis revealed overlapping patterns between ketamine and BPC-157 effects on Nos1 (neuronal NOS), Nos2 (inducible NOS), Plcg1, Prkcg, and Ptgs2 (COX-2)

These processes are essential to how the body repairs damaged tissues, rebuilds connective structures, and restores functional integrity following injury or strain

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