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Inflammation 2017;40:196774

Harris KL, Banks LD, Mantey JA, Huderson AC, Ramesh A

The gut microbiota shapes a diverse pool of BAs, including FXR agonists (e.g., CDCA) and antagonists or modulators (e.g., taurine--muricholic acid (T-MCA) in mice, glycoursodeoxycholic acid (GUDCA) in humans, isoDCA), adding regulatory complexity (55, 88, 89)

In the CNS of HIV-infected patients, the macrophage/microglia are mostly deactivated under the control of cytokines such as TGF-, although in some cases HIVE occurs parallel to the production of proinflammatory cytokines and high viral production at advanced stage of the disease