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When GSH is depleted or when oxidised GSSG accumulates, cells experience damage that accelerates ageing, inflammation, and chronic disease

This is not to say that all genetic associations in T1D are due to mutations in HLA genes as more than 40 additional T1D susceptibility loci have been identified that are not HLA genes

In practice, the injection is administered in a clinical setting by a nurse or physician because it must be given via IV or IM route and monitored

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Gojkovic S., Krezic I., Vranes H., Zizek H., Drmic D., Batelja Vuletic L., Milavic M., Sikiric S., Stilinovic I., Simeon P., et al