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An EFSA-commissioned study conducted in 16 EU member states and involving some 32,000 participants found that 68% of adolescents use EDs (with reported percentages of 30% in adults and 18% in children) [3]

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The adverse effects associated with both pregabalin and gabapentin that have been most commonly reported include dizziness, headache, somnolence, and edema

22.0% in the placebo group) in the primary composite endpoint of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, coronary revascularization, or unstable angina in patients with established ASCVD or with diabetes and other risk factors [65]