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These results demonstrate that a single small molecule can partially correct the catalytic activity and stability of multiple common G6PD variants

There are two main pathways for cysteine catabolism: one is via its enzymatic breakdown to produce H 2 S and organic intermediates that will serve as carbon sources, and the second is via oxidative metabolism through cysteine dioxygenase (CDO)

The SASP consists of a plethora of secreted factors, including pro-inflammatory cytokines, chemokines, growth factors, and extracellular matrix-degrading proteases, which profoundly influence the tissue microenvironment [56]

doi: 10.1016/B978-0-12-420117-0.00003-7