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A 2 to 4 week break follows most cycles

In stroke models, it reduces hippocampal neuron loss, restores memory, and improves motor coordination by modulating gene expression and reducing inflammation

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The reaction begins when methionine synthase takes a methyl group from active folate (5-methyltetrahydrofolate) and uses methylcobalamin to transfer that methyl group to a naturally occurring amino acid called homocysteine
