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Ca 2+ overload, which is a crucial event in eryptosis, leads to the opening of Ca 2+ -activated K + channel KCa3.1, known as the Gardos channel [90]

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Dr Rupy : So when I was at medical school, the subject of uric acid levels was typically paired with gout, high purine levels in the diet and one of the most ubiquitous drugs, allopurinol, which is used to reduce uric acid levels by inhibiting an enzyme called xanthine oxidase, preventing crystals that can lodge in our joints, causing pain, typically the big toe