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Oxysterols can function as endogenous ligands for LXRs, suppressing a transcriptional program to inhibit LDL uptake and promote cholesterol efflux, thereby maintaining cholesterol homeostasis 49
Previously unreported effects of RSL3, such as degradation of mTOR signaling pathway protein, p70S6K, and reduction of p-NPM1 levels were identified in the present study and warrant further investigation
doi: 10.1177/2633105520907895, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Ross D
The Sin 3A protein is a paired amphipathic helix proteins that is found in humans and it's encoded by the SIN 3A gene
