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Pomalidomide-based PROTACs from 3-fluorophtalic anhydride One of the most widely used strategies for linker attachment in PROTACs is via S N Ar reactions with fluorinated derivatives of thalidomide
Epigenetic modifications within the mitochondria can influence mitochondrial gene expression and function

S., Allkabes, M., Salsini, G., Bonifazzi, C

During those we observed significant MetHb accumulation impacting on liver oxygen delivery and function