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Cell control experiments and analyses demonstrate that glycyrrhizic acid, a known HMGB1 binder, which reduces HMGB1 expression induced by TMAO, can be used to treat the disruption of cell junction proteins (Singh et al., 2019)

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Despite being naturally produced in the body, factors like age, dietary restrictions, or specific health conditions can lead to lower L-carnitine levels,[1] highlighting the potential need for dietary or supplemental intake
