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Potential Long-Term Risks Although AOD-9604 does not increase IGF-1 levels, there are concerns about its long-term metabolic effects, including: Unknown impact on fat metabolism regulation Since AOD-9604 alters fat-burning pathways, researchers are still investigating whether prolonged use could affect natural fat metabolism

The CMS NCCI Policy Manual, effective January 1, 2026, states that a patient being new to the provider isnt sufficient by itself to justify an E/M service on the same date as a minor surgical procedure

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