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Safety reality check: published human safety data is not as robust as for FDA-approved therapies

In more detail, the association between dysbiosis and insulin resistance is thought to be connected with the enhanced intestinal permeability and endotoxemia, associated with chronic low-grade inflammation, along with alterations in microbiota-derived metabolitesincluding short-chain fatty acids (SCFAs), bile acids, and branched-chain amino acids (BCAAs)which collectively may influence glucose homeostasis and energy balance [121]
Kerckhove et al., 2017)

2021 Feb:143:104942
