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Depending on the situation, other medical treatments for lip discoloration or lesions may include: laser therapy light therapy chemical peels cryotherapy medicated ointments, such as 5-fluorouracil and Solaraze A 2018 systematic review in the aloe vera gel niacinamide green tea extract turmeric vitamin C However, the authors note that many of the studies were not large-scale clinical trials, and so more research on this is necessary

Various antimicrobial peptides are being developed to address antibiotic-resistant infections

The traction device can also be used with medical and surgical therapy as it may enhance the benefits from those other treatment options

These treatments are often more intensive and can deliver faster, more noticeable results, especially for stubborn or deep-seated post-inflammatory hyperpigmentation (PIH)