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Description
GSH levels have been shown to decrease with ageing and in several age-related degenerative diseases and AD in particular (Harris et al., 2015)

doi:10.4103/0253-7613.81505

In severe cases, we may consider using the intravenous medication pegloticase (Krystexxa), since it lowers the urate level the most dramatically, and can lead to the fastest shrinkage of the tophus

doi: 10.3390/medicines5030093
