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In a study involving mice fed a high-fat, low-carbohydrate ketogenic diet, the induction of ferroptosis effectively suppressed tumor growth [208]
Following TBI, ferroptosis was confirmed by iron buildup, higher transferrin expression, decreased glutathione peroxidase activity, lipid ROS accumulation, and shrinking mitochondria (Rui et al., 2021
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In vivo , FGF18 is activated and promotes chondrocyte proliferation and ECM synthesis through the PI3K/AKT pathway
