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Molecular immune mechanism of intestinal microbiota and their metabolites in the occurrence and development of liver cancer

These properties allow peroxynitrite to significantly alter the function of a considerable number of proteins, to degrade membrane structure by peroxidizing lipids, to turn off crucial metabolic functions within mitochondria, and to inflict serious damage to nucleic acids, activating a major pathway of cell injury and inflammation orchestrated by the nuclear enzyme PARP

Further elucidation of the mechanisms by which gut microbiota influence neuroinflammation and mood, potentially leading to probiotic or prebiotic interventions for depression

is supported by a Physician Services Incorporated Research Trainee Fellowship and a Canadian Institutes of Health Research Canada Graduate Scholarships Doctoral Award