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Oral B12 supplements are convenient, affordable, and effective for mild deficiency or long-term maintenance when digestion and absorption are normal

In any case, this point is very important, because within cells the pool of GSH is 300 to 800 times greater than that of GSSG, therefore, even minimal artifactual or artificial oxidation of GSH can induce a dramatic increase in GSSG, without reflecting a true alteration in the cellular redox state, but even more so without indicating how this redox state can be affected by the health condition or disease that the patient presents

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Tuft cells are a distinct lineage that arise from stem cells in the located in the crypts and comprise approximately 0.4% of epithelial cells (89)