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2 amount in the mesophyll (Gupta et al., 2016), and other physiological responses as shown in Figure 1

Funding This work was supported by the National Key R&D Program of China (grant number: 2023YFC3404100, 2023YFC2506400), and National Natural Science Foundation of China (grant number: 82325042, 82203860), and Shanghai Municipal Education Commission Scientific Research Innovation Project (grant number: 2023-05-50), Wu Jieping Medical Foundation Research Project (grant number: 32067502023-18-29)

3.2 Syndromes caused by expansion of DNA 3.2.1 Friedreichs ataxia Friedreich ataxia (FRDA) is a rare autosomal-recessive neurodegenerative and cardiac disorder characterized by progressive limb and gait ataxia, dysarthria, dysphagia, loss of deep tendon reflexes, oculomotor dysfunction, and cardiomyopathy, with additional symptoms like diabetes mellitus and defective hearing in some cases