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8 The most significant change was that the threshold for overt Stage 1 hypertension dropped from 140/90 mm Hg to 130/80 mm Hg
"Critic's Notebook

doi: 10.1113/jphysiol.2013.251629
Pipecolate is further converted by pipecolic acid oxidase into piperideine-6-carboxylate (P6C), which can be spontaneously converted to AASA and enter the saccharopine pathway