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Advanced molecular studies reveal that FOXO4-DRI promotes p53 nuclear exclusion and subsequent mitochondrial targeting, where p53 interacts with BCL-2 family proteins to promote mitochondrial outer membrane permeabilization and cytochrome c release

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Based on a Houston Chronicle investigation analyzing data from 2001-2016, the Houston region tops the list of the most fatal drunken driving crashes compared to any other large metro area in the United States