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It is also found in foods such as meats, fish, nuts, beans, spinach and eggs

Participates in the metabolism of proteins, fats, amino acids, purines, tissue respiration, glycogenolysis, helps to resist infectious diseases, has detoxifying properties, is rapidly distributed in tissues and passes through the placental barrier

Notably, other related biomarkers like isofurans (IsoFs), which are preferentially formed under high oxygen tensions, complement F2-IsoPs by providing additional information about oxygen-dependent lipid peroxidation (Milne et al., 2013)

While GPX3 localized mainly to the basement membrane of the bronchial epithelium and endothelium in healthy mouse and human tissue, we found localization also to the interstitial ECM in fibrotic tissue compartments