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(285), utilizing UK Biobank data from 33,441 individuals with hyperglycemia (including 7,969 with T2DM) over a median 12.3-year prospective follow-up, found that the highest compared with the lowest Alternate Mediterranean Diet (AMED) score was associated with a 21% reduction in DKD risk (HR = 0.79, 95% CI: 0.670.94)

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Haploinsufficiency Partial deficiency of a protein, resulting from a loss-of-function mutation in one of the two alleles encoding the protein