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MtDNA and ROS are involved in the transcriptional regulation of immune cells

Considering the current literature, interpreting outcomes of Bev has been complicated by the variability in treatment protocols among various studies, to where definitive conclusions cannot be clearly drawn

PMID: 21605659 Rushworth GF, Megson IL

The GAP index score will likely be heavily weighted towards 3 given the availability of pirfenidone and nintedanib