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Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a mg/m2 basis) for two years

Validation of a modified model of TNBS-induced colitis in rats

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Subsequent cellular invasion (internalization) of the pathogen takes place as the viral S-protein/host receptor complex is primed by furin cleavage at two sites: S1/S2 and S2