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Optimizing B12 levels may help support more consistent serotonin synthesis even during periods of reduced sunlight

This cycle of ROS generation and lipid peroxidation perpetuates oxidative injury, worsening inflammation, vascular permeability, and respiratory dysfunction in ARDS patients (91)

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Having assessed that paclitaxel per se, and not its vehicle Cremophor EL, is the main responsible for anaphylactoid reactions induced by the chemotherapy treatment in vivo, we demonstrated that C5aR1 as a crucial factor in the pathophysiology of HSRs induced by paclitaxel and can thus be a potential pharmacological target for their prevention and blockade