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Statins also decreased the cholesterol level and inhibited proteasome action as well as the production of nitric oxide and ROS 121,122,123

Zhonghua Nan Ke Xue = Natl J Andrology
Amikacin is a frequently used aminoglycoside antibiotic in the treatment of peritoneal dialysis-related peritonitis, but ototoxicity is a well-known complication
ROS derived from xanthine oxidase are pivotal for regulating the activation of NLRP3 inflammasome in macrophages [290]
