glutathione reduced vs oxidized states Disulfide - an overview L-Glutathione oxidized
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The redox effects of GSH or other thiol agents can be assessed by the use of irreversible thiol alkylating agents such as N-ethyl maleimide (NEM) which would form covalent bonds with cysteine residues and prevent further modification of these sites as has been analyzed in modulation of GABA- and glycine-evoked currents in rat retinal ganglion cells (24)
doi: 10.7314/APJCP.2015.16.12.4803
Cochlear damage due to cisplatin is primarily found in the organ of Corti, including the hair cells, spiral ganglions, and stria vascularis 10,21
