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Histone modification Histones modification, such as methylation, demethylation, acetylation and deacetylation, remodels the chromatin architecture which dictates histones either loosening or tightening their grip onto DNA to regulate MSC self-renewal, senescence and differentiation potential
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doi: 10.1016/j.clp.2016.04.001

Scar improvement often responds to higher concentrations applied specifically to scarred areas
