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The debate is still open: some studies have reported a null or harmful effect of supplementation with FA and B vitamins, including cyanocobalamin [10], while others have confirmed a link between the homeostasis of the vitamins, cardiovascular risk and CKD progression [12]
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[ 4 ] Some small human studies reported improvements in sleep efficiency and sleep latency in chronic insomniacs, though the effects were described as weak and not consistently different from placebo
