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They cause an imbalance between specific groups of bacteria and trigger the development of dysbacteriosis (Tulstrup et al., 2015)

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Without published relative bioavailability data for the specific peptide via the nasal route, a simple dose conversion is guesswork

One promising therapeutic strategy involves targeting proteins that become upregulated in the DAM, such as TREM2, chemokine receptor CX3CR1, or adenosine A 2A receptors, with the goal of modulating their activation state
