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This leads to DNA damage, checkpoint activation and focal accumulation of the DNA response proteins

Nature 411:10651068

Future studies should incorporate mechanism-relevant biological markers, including serum BDNF to index neurotrophic signaling, inflammatory markers such as CRP and IL-6, measures of HPA-axis activity such as the cortisol awakening response, and neuroimaging markers (e.g., fMRI-based assessments of hippocampal connectivity), to more precisely characterize treatment response and patient stratification

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