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SR-B1 blockade diminishes cholesterol uptake and accumulation in cells, and triggers lipid oxidative stress by reducing the expression of GPX4, leading to ferroptosis
Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA

Alcohol Use Disorder, Neurodegeneration, Alzheimers and Parkinsons Disease: Interplay Between Oxidative Stress, Neuroimmune Response and Excitotoxicity
PMID: 34961563 Click image to see more details Effects of MCTR1 on ferroptosis in CLP-induced AKI
